Dave Song, Ph.D.

Assistant Professor of Chemistry

he/him/his

Assistant Professor David Song

Office Location: Rieke Science Center

Curriculum Vitae: View my CV

  • Professional

Education

  • Ph.D., Chemistry and Chemical Biology, Harvard University, 2024
  • A.M., Chemistry and Chemical Biology, Harvard University, 2014
  • B.S., Chemistry and Molecular & Cellular Biology, University of Illinois at Urbana-Champaign, 2010

Selected Presentations

  • American Chemical Society: Many Flavors of Chemistry. Symposium to Celebrate 2024 ACS National Award for Creative Work in Fluorine Chemistry, Fluorinated tyrosines (Y) and tryptophans (W): Probes of the radical transfer process in class Ia E.coli ribonucleotide reductase (RNR) (March 2024)
  • Northeast Regional Meeting of the American Chemical Society, Radical transport pathway of ribonucleotide reductase, Boston, MA (June 2023)
  • Canadian Chemistry Conference and Exhibition, PCET in Ribonucleotide Reductase, Synthesis and Electrochemistry of Unnatural Tryptophan Analogues, Vancouver, BC, Canada (June 2023)
  • ACS Spring 2023: Crossroads of Chemistry, Proton transfer network at the subunit interface of ribonucleotide reductase supports radical transport, Indianapolis, IN and virtual (March 2023)

Selected Articles

  • Song, D. Y.; Stubbe, J., Nocera, D.G. . "Protein engineering a PhotoRNR chimera based on a unifying evolutionary apparatus among the natural classes of ribonucleotide reductases." Proceedings of the National Academy of Sciences of the USA Vol. 121, 2024:
  • . Cui, C.; Song, D. Y.; Drennan, C. L.; Stubbe, J.; Nocera, D. G.. "Radical Transport Facilitated by a Proton Transfer Network at the Subunit Interface of Ribonucleotide Reductase." Journal of the American Chemical Sciences Vol. 145, 2023: 5145-5154.
  • Song, D. Y.; Pizano, A. A.; Holder, P. G.; Stubbe, J.; Nocera, D. G. . "Direct interfacial Y731 oxidation in ╬▒2 by a photo╬▓2 subunit of E. coli class Ia ribonucleotide reductase." Chemical Science Vol. 6, 2015: 4519-4524.
  • Tripathi, V.1 ; Song, D. Y.1 ; Zong, X.; Shevtsov, S. P.; Hearn, S.; Fu, X. D.; Dundr, M.; Prasanth, K. V.. "SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles." Molecular Biology of the Cell Vol. 23, 2012: 3694-706.
  • Tripathi, V.; Ellis, J. D.; Shen, Z.; Song, D. Y.; Pan, Q.; Watt, A. T.; Freier, S. M.; Bennett, C. F.; Sharma, A.; Bubulya, P. A.; Blencowe, B. J.; Prasanth, S. G.; Prasanth, K. V.. "The NuclearRetained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation." Molecular Cell Vol. 39, 2010: 925-938.

Accolades

  • Student Recognition of Teaching Certificate, Harvard University 2022
  • National Science Foundation Graduate Research Fellowship 2013
  • Department of Chemistry Award for Outstanding Teaching, MIT 2012
  • Howard Hughes Medical Institute Teaching Assistant Fellowship, MIT 2011
  • Lewis Paul Chapin Fellowship, MIT 2011